This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate …

The Antibody Society maintains a comprehensive list of approved antibody therapeutics and those in regulatory review in the European Union (EU) or United States (US).

Amgen’s denosumab, a first-in-class monoclonal antibody that is specific for receptor activator of nuclear factor-κB ligand (RANKL), was first approved in June 2010 in the United States for...

Eight years later, in 1992, the US FDA approved the first therapeutic mAb muromonab-CD3 (trade name Orthoclone OKT3) to reduce acute rejection in patients with organ transplants. Since then, as of …

Jun 2, 2025 · A collection of biological approval information organized by year and regulatory authorities.

Nov 27, 2025 · Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.

The Antibody Society continuously collects data for approved antibody therapeutics and those in regulatory review in any country. A searchable table of this data is below.

Jan 21, 2025 · The antibody is in development by Merus as a treatment for patients with solid tumors harboring NRG1 gene fusions (NRG1+ cancer), who typically have suboptimal responses to …

Jan 12, 2017 · Therapeutic monoclonal antibodies approved or in review in the European Union or the United States The Antibody Society maintains a comprehensive table of approved ant. body …

Nov 18, 2025 · Monoclonal antibodies are usually genetically modified antibodies. They are used both in diagnostics and in therapies, and here, in particular in immune suppression and cancer therapy. The …