Structure and Function of Major SARS-CoV-2 and SARS-CoV ...
Coronaviruses contain a positive-sense RNA genome, which is wrapped up in helical nucleocapsid. The genome size of SARS-CoV-2 is about 30 kb. Among the RNA viruses, coronaviruses have the …
Coronavirus spike protein - Wikipedia
Spike glycoprotein from SARS-CoV-2. PDB: 6VSB. Only one monomer is highlighted. Whole protein is a homotrimer. Rest of the trimer is shown as a gray surface. Parts of the actual structure are not …
The Helix Viral Sequencing Assay
Jan 10, 2022 · Helix has led scientific efforts to track and understand the evolution of SARS-CoV-2. This is a snapshot of Helix’s viral sequencing pipeline along with an assessment of its performance. …
SARS-CoV-2 Structure & Genome: Key Proteins & RNA Features
Jan 11, 2025 · Explore the structure and genome of SARS-CoV-2, detailing its RNA composition and key structural proteins like spike, envelope, membrane, and nucleocapsid.
BPS2025 - Structural insights into SARS-CoV-2 fusion domain ...
Feb 13, 2025 · In conclusion, SARS-CoV-2 FD promotes more efficient fusion in a low pH environment with BMP, leveraging subtle structural changes, including helix 1 extension, to exploit altered …
Mechanisms of SARS-CoV-2 entry into cells - Nature
Oct 5, 2021 · Much of this response has focused, appropriately, on the mechanisms of SARS-CoV-2 entry into host cells, and in particular the binding of the spike (S) protein to its receptor,...
Designing a broad-spectrum four-helix bundle targeting ...
Jun 6, 2025 · One major strategy for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to evade antibody drugs or preventive vaccines is high mutation rate of the spike receptor binding …